Home » Adam Olshen

Personal Profile of Adam B. Olshen

Adam B. Olshen

• Talks

1. October 24, 2007 - October 26, 2007

   Workshop Mathematical Systems Biology of Cancer II

   Show All Collapse

   Oct 26, 2007 Friday

   04:15 PM - 05:00 PM   Segmentation of Array CGH Data with Application to Allele Specific Copy Number, Clonality, and Copy Number Variation Adam Olshen Location -- Video -- Abstract Cancer progression often involves alterations in DNA sequence copy number. Multiple microarray platforms now facilitate high-resolution copy number assessment of entire genomes in single experiments. This technology is generally referred to as array comparative genomic hybridization (array CGH). I will discuss our technique for identifying regions of abnormal copy number in array CGH data, which is called circular binary segmentation (CBS). The first published version of CBS was criticized for being slow. I will present our methods for greatly speeding up the procedure. I will also show our approaches to recent copy number applications including allele-specific copy number, clonality, and copy number variation. This is joint work with E.S. Venkatraman. Supplements -- Show Detail

2. February 09, 2004 - February 13, 2004

   Workshop Genetics of Complex Disease

   Show All Collapse

   Feb 09, 2004 Monday	08:00 AM - 05:00 PM   Haplotype Block Parition and its applications to association studies Fengzhu Sun Location -- Video Abstract -- Supplements -- Show Detail